Photostimulation
Max. emission energy 467 nm: 10 J/min.
Max. emission energy 530 nm: 10 J/min.
Max. emission energy 591 nm: 7.5 J/min.
Max. emission energy 620 nm: 12 J/min.
Max. emission energy 850 nm: 10 J/min.
Significantly increase the concentration of autologous exosomes, growth factors, and ATP in any plasma product with MCT. Using advanced temperature and light modulation, the MCT Unit® supercharges PRP, amplifying its regenerative potential and unlocking enhanced treatment benefits. Designed for seamless integration into any existing PRP protocols, the easy-to-use MCT system elevates your PRP treatments for better patient outcomes.
Autologous Exosomes
Cell and platelet photothermal
conditioning stimulates exosome production and release, resulting in enhanced regenerative potential.
Growth Factor Delivery
The amount of growth factors released substantially increases when platelets are photothermally stimulated. This happens in a more physiological way, which means that not only the “flush” delivery increases, but a more “sustained” release takes place as well.
ATP Synthesis
When mitochondria are exposed to the proper wavelength of light, the boost of energy alters their electron state. To recover energetic equilibrium, mitochondria alter their trans-membrane proton gradient, which will ultimately lead to a huge increase in ATP production.
Platelet Performance
MCT primes platelets to function more effectively. This is why the MCT Kit® can work with any type of plasma and any commercial kits for PRP procurement. MCT does not concentrate platelets; it exposes them to photothermal conditioning protocols.
Reduced Discomfort
Thermal conditioned MCT Plasma is less dense than standard PRP. A more fluid plasma promotes less pain at the site of injection resulting in a better patient experience.
Dr. Jasmina Kozarev (Dermatovenerologist, MD, MSc, PhD)
Dr. Jasmina Kozarev (Dermatovenerologist, MD, MSc, PhD)
Dr. Jasmina Kozarev (Dermatovenerologist, MD, MSc, PhD)
MCT enhances regenerative medical treatments through the simultaneous application of electromagnetic and thermal energy to autologous liquid materials, such as PRP. Photothermal stimulation is a non-toxic, non-invasive way to influence cell signaling pathways and exosome secretion kinetics to promote tissue regeneration.
Temperature modulation plays a pivotal role in cellular and platelet function. Low temperatures (4 °C) prime platelet activation and enhance the release of growth factors (VEGF, EGF, and bFGF), while higher temperatures (37 °C) induce exosome release, leading to higher concentrations of autologous exosomes in the injectable material.
Temperature directly influences exosome secretion kinetics with more exosomes released at higher temperatures.
MCT applies specific wavelengths of light with precise power and timing to optimize the biological response.
Growth factor concentrations in PRP pre thermal conditioning (4 ˚C for 10 minutes) and post thermal conditioning.
Autologous material directly exposed to light profoundly affects chromophores, including cytochrome C oxidase and opsins, activating secondary messengers (COS, Ca2+, ATP, cAMP, NO), thereby modulating cell signaling pathways.
The effect of light and temperature on membrane proteins as an example of how cell signaling pathways are modulated.
MCT Unit® enhances existing regenerative medicine treatments, simply and quickly. Through the application of electromagnetic and thermal energy, it improves the general characteristics of autologous products, such as growth factor content, ATP production, and cell or platelet performance. It handles a wide range of temperatures and multiple wavelengths which are set up in one-touch, customized programs.
MCT Kit® is a patented device with a specific shape and chemical composition, exclusively developed for photothermal conditioning. It is made of a medical-grade polymer that guarantees optimal scattering, transmittance, and optical properties to ensure the emitted light is applied to the target effectively. Its unique geometry grants an excellent surface-to-volume energy exposure ratio. The MCT Kit® can hold 10 mL of any autologous preparate.